Graduate/faculty Seminar
Friday, November 1, 2013, 4:30pm, 119 Physics
Ioannis Sgouralis
Renal autoregulation in a dynamic nephrovascular model
Abstract:- Renal autoregulation stabilizes kidney functions and provides
protection against blood pressure fluctuations. Autoregulation is mediated
by two mechanisms: the *myogenic response,* where increased blood pressure
elicits vascular constriction, and *tubuloglomerular feedback,* where salt
excretion is balanced by adjustments of filtration rate. Coupling of the
two mechanisms give rise to complex behaviours that are challenging to
analyse. In the talk, I will describe a mathematical model of renal
autoregulation, which represents both mechanisms and thus can be used to
study the interactions developed among them. I will provide the necessary
physiological background, and I will focus on the mathematical formulation
of the involved processes. The talk will be accessible to everyone with
basic understanding of differential equations. [video]
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